The Watford striker last played for Nigeria in 2017.
Super Eagles’ technical adviser Gernot Rohr also called up Alex Iwobi and Moses Simon for the clash against the Mediterranean Knights.
Goalkeeper Ikechukwu Ezenwa is the only home-based Eagle invited.
The team will go into the game seeking six maximum points against the Group E leaders.
Nigeria will host the first leg at the Godswill Akpabio Stadium in Uyo on October 13 while the return is scheduled for October 16 at Stade Taïeb Mhiri, Tunisia.
The invited Eagles
Goalkeepers: Francis Uzoho (Elche FC, Spain); Ikechukwu Ezenwa (Enyimba FC); Daniel Akpeyi (Chippa United, South Africa)
Defenders: Olaoluwa Aina (Torino FC, Italy); Abdullahi Shehu (Bursaspor FC, Turkey); Semi Ajayi (Rotherham United, England); Bryan Idowu (Lokomotiv Moscow, Russia); Chidozie Awaziem (FC Porto, Portugal); William Ekong (Udinese FC, Italy); Leon Balogun (Brighton & Hove Albion, England); Kenneth Omeruo (CD Leganes, Spain); Jamilu Collins (SC Padeborn 07, Germany)
Midfielders: Ogenyi Onazi (Trabzonspor FC, Turkey); Wilfred Ndidi (Leicester City, England); Oghenekaro Etebo (Stoke City FC, England); John Ogu (Hapoel Be’er Sheva, Israel)
Forwards: Ahmed Musa (Al Nasr FC, Saudi Arabia); Kelechi Iheanacho (Leicester City, England); Moses Simon (Levante FC, Italy); Henry Onyekuru (Galatasaray SK, Turkey); Odion Ighalo (Changchun Yatai, China); Alex Iwobi (Arsenal FC, England); Samuel Kalu (Bordeaux FC, France); Isaac Success (Watford FC, England)